Primary Hyperhidrosis: A Review of Epidemiology, Pathophysiology and Management

Alexander Shayesteh · 2026

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Description

Alexander Shayesteh reviews primary hyperhidrosis, the condition of sweating far beyond what the body needs to control temperature. Drawing on a literature search run in June 2026, the review covers how common the condition is, how it develops, what it costs, and how it is diagnosed and treated. Reported prevalence varies widely between studies, which the author links to weak recognition and differing methods.

The condition is tied to overactive sympathetic nerve signaling to sweat glands, with hints that gland changes and inherited differences in receptor levels shape severity. Its burden on daily life, mental health, and work is heavy. Treatments range from topical products and tablets to devices, botulinum toxin injections, and surgery, but the review notes that long-term costs and wider social effects are still poorly measured.

Catalog record

CREATORAlexander Shayesteh
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13579654

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