Phenotype-driven cascade screening in a Syrian family with clinically consistent multiple endocrine neoplasia type 2A
Munawar Hraib, Mona Alturun, Taim Al Kheder, Faozat Alonainy · 2026
Read Phenotype-driven cascade screening in a Syrian family with clinically consistent multiple endocrine neoplasia type 2A by Munawar Hraib, Mona Alturun, Taim Al Kheder, Faozat Alonainy (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13579058.txt.
Description
Four doctors report cascade screening in a Syrian family with a hereditary tumor syndrome in a 2026 paper. The syndrome, MEN2A, runs in families and brings thyroid cancer, adrenal tumors, and parathyroid overgrowth. Finding it early lets doctors screen kin before disease advances.
The first patient, a 37 year old man, had both adrenal glands and his thyroid removed, and pathology confirmed the classic tumor pair. Screening by symptoms and labs, without gene testing, then found his 39 year old sister with the same tumor pair. A younger brother held two distinct thyroid cancers of other types. The family shows the value of symptom driven screening where gene tests are lacking.
Catalog record
| CREATOR | Munawar Hraib, Mona Alturun, Taim Al Kheder, Faozat Alonainy |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |