Cough hypersensitivity risk increases during heatwaves and can be reduced by inhalation of alkaline aerosols of endogenous ions

B Button, A Edwards, K F Chung, H Dang, M Gutay, N Griffin, J Gerenza, Linying Wang, H Abubakar-Waziri, D B Bhatta, D A Ausiello, D Li, B Alotaibi, K K Altassan, D A Edwards · 2026

Read Cough hypersensitivity risk increases during heatwaves and can be reduced by inhalation of alkaline aerosols of endogenous ions by B Button, A Edwards, K F Chung, H Dang, M Gutay, N Griffin, J Gerenza, Linying Wang, H Abubakar-Waziri, D B Bhatta, D A Ausiello, D Li, B Alotaibi, K K Altassan, D A Edwards (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13578754.txt.

Description

B Button and co-authors report in this 2026 study that heatwaves can prime airways for coughing fits, and that a salty alkaline mist can undo it. Dry heat, they show in lab-grown airway cells, collapses the airway surface layer and switches on cough-linked sensor genes after eight hours. A mechanics model predicted that alkaline aerosols of natural salts would reopen the layer, but only above a sharp acidity threshold.

Cell tests confirmed the threshold. In small human trials in Riyadh, the alkaline mist at the higher strength cut daily cough bouts by about fifty-nine percent in two weeks versus placebo, while a weaker mix barely helped. The authors propose the spray as heatwave protection.

Catalog record

CREATORB Button, A Edwards, K F Chung, H Dang, M Gutay, N Griffin, J Gerenza, Linying Wang, H Abubakar-Waziri, D B Bhatta, D A Ausiello, D Li, B Alotaibi, K K Altassan, D A Edwards
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE53 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13578754

Browse the full library · About the Tower of Babel