A prospective randomized controlled pilot study of gut microbiome modulation by Nigella sativa seed oil and thymoquinone metabolism in healthy volunteers: implications for gastrointestinal surgery
Ahmad Firas El-Banna, Howard Junca, Arndt Steube, Dirk K Wissenbach, Utz Settmacher, Claus Schneider, Aysun Tekbaş · 2026
Read A prospective randomized controlled pilot study of gut microbiome modulation by Nigella sativa seed oil and thymoquinone metabolism in healthy volunteers: implications for gastrointestinal surgery by Ahmad Firas El-Banna, Howard Junca, Arndt Steube, Dirk K Wissenbach, Utz Settmacher, Claus Schneider, Aysun Tekbaş (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13578717.txt.
Description
Seven authors run a pilot trial of black seed oil in healthy volunteers in this 2026 study. The oil, from Nigella sativa seeds, carries a compound called thymoquinone with antimicrobial and immune effects, and gut microbe balance may shape outcomes in gut surgery.
Eight adults were randomized, four to oil capsules three times a day for twenty days and four to no supplement. Stool samples at five time points were sequenced, food diaries were kept, and urine was tested for the compound and its breakdown products. Overall microbe diversity did not differ firmly between groups in this tiny pilot. The study mainly tests whether such a trial can be run and measured well.
Catalog record
| CREATOR | Ahmad Firas El-Banna, Howard Junca, Arndt Steube, Dirk K Wissenbach, Utz Settmacher, Claus Schneider, Aysun Tekbaş |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |