CellSearch-based isolation of circulating tumor cells from ascitic fluid enables molecular characterization of ovarian cancer
Francesca Gorini, Thais Maloberti, Emma Coschina, Francesco Mezzapesa, Biljana Petrovic, Giulia Gallerani, Manuela Ferracin, Elisa Scarpelli, Antonio De Leo, Ivana Kurelac, Pierandrea De Iaco, Sabrina Angelini, Anna Myriam Perrone, Dario de Biase, Gloria Ravegnini · 2026
Read CellSearch-based isolation of circulating tumor cells from ascitic fluid enables molecular characterization of ovarian cancer by Francesca Gorini, Thais Maloberti, Emma Coschina, Francesco Mezzapesa, Biljana Petrovic, Giulia Gallerani, Manuela Ferracin, Elisa Scarpelli, Antonio De Leo, Ivana Kurelac, Pierandrea De Iaco, Sabrina Angelini, Anna Myriam Perrone, Dario de Biase, Gloria Ravegnini (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13578618.txt.
Description
Francesca Gorini and co-authors test whether tumor cells floating in belly fluid can reveal the biology of a severe ovarian cancer. This cancer often spreads with a build-up of fluid in the belly, and that fluid is rich in tumor cells. By contrast, tumor cells in the blood are often too scarce to study.
The team paired blood and fluid samples from twelve patients at surgery and ran them through a standard cell-capture system. They counted the captured cells, then pulled DNA from the fluid-derived cells for study. The fluid route gave enough material to read the cancer's gene traits. That could open a new window for tracking this cancer and matching patients to treatments.
Catalog record
| CREATOR | Francesca Gorini, Thais Maloberti, Emma Coschina, Francesco Mezzapesa, Biljana Petrovic, Giulia Gallerani, Manuela Ferracin, Elisa Scarpelli, Antonio De Leo, Ivana Kurelac, Pierandrea De Iaco, Sabrina Angelini, Anna Myriam Perrone, Dario de Biase, Gloria Ravegnini |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |