Multiomics analyses revealed the roles of the epithelial–mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis
Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He · 2026
Read Multiomics analyses revealed the roles of the epithelial–mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis by Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13578613.txt.
Description
Xiao-Chen Liu led a team of thirteen that studied, in two thousand twenty-six, a grave gut ill of newborn babes. The ill is necrotising enterocolitis, in short NEC. In it, gut tissue dies. Why it starts is not fully known, and doctors lack firm early signs to spot it in time.
The team joined many ways to read tissue at once: proteins in bulk and by place, and the RNA of single cells. They checked finds with stains, blood tests, and a mouse form of the ill. One theme ran through the reads. Gut lining cells took on traits of deep cells, a shift known as the epithelial-mesenchymal transition. In mice, a drug that blocks that shift eased gut harm and death. Four proteins stood out as tissue signs. One, ANXA2, was high in blood too, with a score of 0.944 for spotting the ill.
Catalog record
| CREATOR | Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |