Treatment patterns and healthcare resource utilization in pediatric neurofibromatosis type 1-associated symptomatic plexiform neurofibroma in the United States from 2000 to 2019
Surya P Rednam, Theresa Dettling, Michael Blackowicz, Randolph de la Rosa Rodriguez, Xiaoqin Yang, Saima Ali, Julia Meade · 2026
Read Treatment patterns and healthcare resource utilization in pediatric neurofibromatosis type 1-associated symptomatic plexiform neurofibroma in the United States from 2000 to 2019 by Surya P Rednam, Theresa Dettling, Michael Blackowicz, Randolph de la Rosa Rodriguez, Xiaoqin Yang, Saima Ali, Julia Meade (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13578489.txt.
Description
Surya P Rednam and colleagues chart the care load for children with nerve sheath tumors tied to a genetic condition, in a 2026 United States chart review. The condition, called NF1, leads many patients to grow plexiform tumors along nerves. Such growths often cannot be cut out safely. Records for 102 children came from three centers, covering care from 2000 through 2019.
Each child grew about three to four problem tumors on average. Pain hit three quarters of the group, and nearly half faced changes in appearance. Surgery was tried in over a third, yet most tumors grew back within a year or more of follow up. Children averaged six clinic visits a year and several scans a year. The review predates new drug approvals, and it frames the gap those drugs must fill.
Catalog record
| CREATOR | Surya P Rednam, Theresa Dettling, Michael Blackowicz, Randolph de la Rosa Rodriguez, Xiaoqin Yang, Saima Ali, Julia Meade |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38175 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |