Leishmanicidal efficacy of cold atmospheric multiple plasma jet against Leishmania major in a murine model: effects on parasite burden, cytokine profiles, and wound healing
Elham Rezaee, Gholamreza Hatam, Kamiar Zomorodian, Bahador Sarkari, Naghmeh Dastan, Amin Shamsaei, Zahra Gheibi, Hamed Taghvaei · 2026
Read Leishmanicidal efficacy of cold atmospheric multiple plasma jet against Leishmania major in a murine model: effects on parasite burden, cytokine profiles, and wound healing by Elham Rezaee, Gholamreza Hatam, Kamiar Zomorodian, Bahador Sarkari, Naghmeh Dastan, Amin Shamsaei, Zahra Gheibi, Hamed Taghvaei (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13578423.txt.
Description
Elham Rezaee and co-authors zap a parasitic skin disease with cold plasma instead of drugs. Cutaneous leishmaniasis, spread by sandflies, resists treatment as drugs grow toxic or fail. A cold atmospheric plasma jet showers tissue with reactive oxygen and nitrogen species that kill microbes and stir immunity. Infected mice received the jet for five, ten, or fifteen minutes, twice weekly for three weeks, alongside drug and untreated controls.
Lesions shrank significantly under plasma treatment, most at fifteen minutes. Parasite loads in the spleen fell across all plasma groups, again lowest at the longest dose. Immune signals tilted toward the Th1 pattern that fights the parasite. The authors present the jet as a drug-free candidate for a neglected disease, with dose clearly mattering.
Catalog record
| CREATOR | Elham Rezaee, Gholamreza Hatam, Kamiar Zomorodian, Bahador Sarkari, Naghmeh Dastan, Amin Shamsaei, Zahra Gheibi, Hamed Taghvaei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |