Impact of adenosine in controlled aortic root reperfusion on clinical outcomes among patients undergoing valvular heart surgery
Farshad Jalili Shahandashti, Naser Kachoueian, Mostafa Fattahi, Davoud Samaie, Maryam Ghanbari Garekani, Atefeh Taherkhani, Seyedehmasoumeh Seyedebrahimi, Saied Heydari Nia, Farhad Gorjipour, Fazel Gorjipour · 2026
Read Impact of adenosine in controlled aortic root reperfusion on clinical outcomes among patients undergoing valvular heart surgery by Farshad Jalili Shahandashti, Naser Kachoueian, Mostafa Fattahi, Davoud Samaie, Maryam Ghanbari Garekani, Atefeh Taherkhani, Seyedehmasoumeh Seyedebrahimi, Saied Heydari Nia, Farhad Gorjipour, Fazel Gorjipour (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13577647.txt.
Description
Adenosine is a common drug in heart surgery, and some studies link it to better heart function after valve operations. But its role during the reperfusion phase, when blood flow returns to the heart, is still unsettled. The ten authors ran a randomized trial over three months with 60 valve surgery patients, split evenly between two groups. One group received adenosine-enriched reperfusion through the aortic root just before the clamp came off; the other received standard warm blood reperfusion.
Bypass time, clamp time, and time on a ventilator did not differ between groups, and inotropic drug use was similar during surgery and in intensive care. But the adenosine group needed antiarrhythmic drugs in the operating room more often. The control group fared better on antiarrhythmic use, shocks, and rhythm problems, so the paper favors the standard warm blood method for managing rhythm after surgery.
Catalog record
| CREATOR | Farshad Jalili Shahandashti, Naser Kachoueian, Mostafa Fattahi, Davoud Samaie, Maryam Ghanbari Garekani, Atefeh Taherkhani, Seyedehmasoumeh Seyedebrahimi, Saied Heydari Nia, Farhad Gorjipour, Fazel Gorjipour |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |