From sequences to strategies: Early detection of new SARS-CoV-2 variants via genetic distance to reduce hospitalizations
Marika D’Avanzo, Aung Pone Myint, Giacomo Cacciapaglia, Stefan Hohenegger, Francesco Conventi, Marta Nunes, Roger Dimitri Kouyos, Michael Domaratzki, Roger Dimitri Kouyos, Michael Domaratzki, Roger Dimitri Kouyos, Michael Domaratzki · 2026
Read From sequences to strategies: Early detection of new SARS-CoV-2 variants via genetic distance to reduce hospitalizations by Marika D’Avanzo, Aung Pone Myint, Giacomo Cacciapaglia, Stefan Hohenegger, Francesco Conventi, Marta Nunes, Roger Dimitri Kouyos, Michael Domaratzki, Roger Dimitri Kouyos, Michael Domaratzki, Roger Dimitri Kouyos, Michael Domaratzki (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13577520.txt.
Description
Marika D'Avanzo and co-authors build an early warning method for new virus forms in a 2026 study of the virus that caused COVID-19. Health teams need weeks of lead time when a new form starts to spread. The team tracked how far each new form's spike gene sat from past forms.
Their method grouped gene codes from six European countries, week by week, from 2020 to early 2024. About 5,000 codes a week let the team spot new chains in four weeks. A trained model then flagged which chains would take over, three to four weeks out. Gene gaps and control steps both tracked with later hospital loads in the models.
Catalog record
| CREATOR | Marika D’Avanzo, Aung Pone Myint, Giacomo Cacciapaglia, Stefan Hohenegger, Francesco Conventi, Marta Nunes, Roger Dimitri Kouyos, Michael Domaratzki, Roger Dimitri Kouyos, Michael Domaratzki, Roger Dimitri Kouyos, Michael Domaratzki |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |