Analysis of porphyrins from serum and the benefit of inert biphenyl columns for liquid chromatography separation
Moritz Unnerstall, Manfred Fobker, Patrick Christian Opitz, Lukas Helmer, Eric Suero Molina, Simone König · 2026
Read Analysis of porphyrins from serum and the benefit of inert biphenyl columns for liquid chromatography separation by Moritz Unnerstall, Manfred Fobker, Patrick Christian Opitz, Lukas Helmer, Eric Suero Molina, Simone König (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13577369.txt.
Description
Moritz Unnerstall and co-authors improve blood tests for porphyrins, the ring compounds behind heme. Their 2026 paper serves brain surgery work, where one porphyrin glows to mark tumors. Standard liquid separation with a common column type can blur peaks and lose signal for these compounds.
Swapping to an inert biphenyl column sharpened separation and boosted detection for six porphyrins. Those six sit on the heme-building path and matter as side products in glow-guided surgery. Sticky loss of sample on metal parts fell with inert hardware and the new column fill. Chemical coating of parts beat additives for cutting that loss. Plastic tubing with the new column gave the best runs in less time. A Python tool speeds data handling.
Catalog record
| CREATOR | Moritz Unnerstall, Manfred Fobker, Patrick Christian Opitz, Lukas Helmer, Eric Suero Molina, Simone König |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |