Integrin β3 α2,6-sialylation by the sialyltransferase ST6Gal1 promotes human cytomegalovirus entry into fibroblasts
Taowen Pan, Huiyi Wang, Liyuan Guo, Guogan Tang, Luping Zheng · 2026
Read Integrin β3 α2,6-sialylation by the sialyltransferase ST6Gal1 promotes human cytomegalovirus entry into fibroblasts by Taowen Pan, Huiyi Wang, Liyuan Guo, Guogan Tang, Luping Zheng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13577289.txt.
Description
Taowen Pan and colleagues published a laboratory study in two thousand twenty-six on how human cytomegalovirus gets inside fibroblast cells. Their focus was a sugar coating added to a surface protein called integrin beta three. An enzyme named ST6Gal1 attaches that coating, and the team asked whether the virus needs it to enter.
Cells missing the protein or the enzyme let far less virus inside, which the group checked with several lab tests. Without the coating, virus and cell signals failed to connect properly, and a key entry pathway stayed switched off. Readers gain a possible new drug target for a very common virus.
Catalog record
| CREATOR | Taowen Pan, Huiyi Wang, Liyuan Guo, Guogan Tang, Luping Zheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |