Occupational heatstroke-induced acute kidney injury: a narrative review of mechanisms, biomarkers, and the timing of blood purification initiation
Sisi Wang · 2026
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Description
Sisi Wang reviews how occupational heatstroke wrecks kidneys and when doctors should start filtering the blood, in a 2026 article. Outdoor and industrial workers collapse with exertional heatstroke; muscle breakdown floods the blood with myoglobin, a direct kidney poison. From over sixteen thousand records, ninety-five sources fed this synthesis of mechanisms, biomarkers, and treatment timing.
Four injury pathways unfold on different clocks: heat itself, myoglobin-driven cell death, clotting-inflammation spirals, and gut toxins leaking in. One urine marker has direct heat-specific human evidence; a famous intensive care marker pair has none yet here. The review maps the cascade onto a biomarker-guided timetable for purification, since trials in general patients may mislead here.
Catalog record
| CREATOR | Sisi Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 101 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |