Rethinking the immune recognition of cell walls in human fungal pathogens: Mechanisms, controversies and translational significance

Rong Wang, Xiaoyu Peng, Wenqing Liu, Zhangyong Song, Hong Yu · 2026

Read Rethinking the immune recognition of cell walls in human fungal pathogens: Mechanisms, controversies and translational significance by Rong Wang, Xiaoyu Peng, Wenqing Liu, Zhangyong Song, Hong Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13577251.txt.

Description

Wang and co-authors re-think how the host spots the walls of germs that breach skin. Germ walls hold chain sugars that the host reads as threat marks. Two host catch clans, Toll-like and C-type, grab those sugars first. Grabs spark cell eats, signal floods, and threat shows to peers. Help cells then split in Th1, Th2, Th17, and Treg camps. B cells add germ-tied guards and build threat recall for next meets.

The line twixt shield and harm shifts by germ type and host state. Stage of the breach moves that line as much as type. The review maps catch paths, cell roles, and the dual face of both arms. It flags rows and gaps that block drug and shot work. Paths to tune the host wars close the sweep.

Catalog record

CREATORRong Wang, Xiaoyu Peng, Wenqing Liu, Zhangyong Song, Hong Yu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE102 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13577251

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