Multitarget Pharmacological Mechanisms and Safety Profiles of Six Ethnobotanically Prioritized Indonesian Medicinal Plants for Cardiometabolic Disorders: A Systematic Review
Febrina A Saputri, Raden M Febriyanti, Zulfan Zazuli, Callista A Mulyadi, Citra Aulia Rahma, Made A N D Putri, Najwa Kirana · 2026
Read Multitarget Pharmacological Mechanisms and Safety Profiles of Six Ethnobotanically Prioritized Indonesian Medicinal Plants for Cardiometabolic Disorders: A Systematic Review by Febrina A Saputri, Raden M Febriyanti, Zulfan Zazuli, Callista A Mulyadi, Citra Aulia Rahma, Made A N D Putri, Najwa Kirana (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13576854.txt.
Description
Febrina Saputri and six co-authors reviewed six Indonesian medicinal plants long used against diabetes and heart-metabolic disease, in this 2026 systematic review. Sixty-six studies passed screening, spanning computer models, cell tests, animal work, and safety checks. The team sorted the plants' actions across blood sugar, lipids, blood vessels, inflammation, and oxidative stress.
One plant, Gynura procumbens, showed the widest activity and the friendliest short-term safety record. Three others fought diabetes strongly in the lab but carried liver, kidney, or fertility warning signs. Evidence for the last two stayed thin and mostly early-stage. With extracts varying wildly between studies, the authors urge standardized preparations and real clinical trials before any remedy claims.
Catalog record
| CREATOR | Febrina A Saputri, Raden M Febriyanti, Zulfan Zazuli, Callista A Mulyadi, Citra Aulia Rahma, Made A N D Putri, Najwa Kirana |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 80 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |