Single-cell transcriptomics provides insights into the stress-immune interplay and informs disease risk

Sofia Benavides, Oksana Kosyk, Haiyang Wang, Alexander G Bastian, Christina Georgiou, Brian C Miller, Natalie Stanley, Anthony S Zannas · 2026

Read Single-cell transcriptomics provides insights into the stress-immune interplay and informs disease risk by Sofia Benavides, Oksana Kosyk, Haiyang Wang, Alexander G Bastian, Christina Georgiou, Brian C Miller, Natalie Stanley, Anthony S Zannas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13576718.txt.

Description

SummaryEnvironmental stress contributes to many diseases—including cardiovascular disease, mental illness, and autoimmune disorders—through immune dysregulation. Stress operates through the hypothalamic-pituitary-adrenal and sympathoadrenal axes, leading to peripheral secretion of cortisol and norepinephrine. While these stress hormones can profoundly influence immune function, their mechanistic effects at the cell-type level remain poorly understood.

Catalog record

CREATORSofia Benavides, Oksana Kosyk, Haiyang Wang, Alexander G Bastian, Christina Georgiou, Brian C Miller, Natalie Stanley, Anthony S Zannas
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE74 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13576718

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