STAR in a Second: Ultra-High-Dose-Rate Spread-Out Bragg Peak Proton Therapy for Breath-Hold Stereotactic Arrhythmia Radioablation

Pavitra Ramesh, Marco Schwarz, Caroline Colbert, Xinyuan Claire Chen, Neil Panjwani, Stephen R Bowen, Clemens Grassberger, Chen Wei, Uyanga Batnyam, Babak Nazer, Matthew J Nyflot · 2026

Read STAR in a Second: Ultra-High-Dose-Rate Spread-Out Bragg Peak Proton Therapy for Breath-Hold Stereotactic Arrhythmia Radioablation by Pavitra Ramesh, Marco Schwarz, Caroline Colbert, Xinyuan Claire Chen, Neil Panjwani, Stephen R Bowen, Clemens Grassberger, Chen Wei, Uyanga Batnyam, Babak Nazer, Matthew J Nyflot (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13576714.txt.

Description

Pavitra Ramesh and co-authors tested a fast proton therapy plan for dangerous heart rhythms in two thousand twenty-six. The treatment, called STAR, uses radiation to ablate heart tissue that causes ventricular tachycardia. Breathing and heartbeat motion usually force large margins or slow gated delivery.

They re-planned five past cases with ultra-high-dose-rate protons shaped by a custom modulator. Each beam could be delivered in about a second, within a single breath hold. Target coverage matched the quality of the clinical photon plans, and doses to the heart, esophagus, and stomach were reported. The authors say the speed offers a way to manage motion without long treatment times.

Catalog record

CREATORPavitra Ramesh, Marco Schwarz, Caroline Colbert, Xinyuan Claire Chen, Neil Panjwani, Stephen R Bowen, Clemens Grassberger, Chen Wei, Uyanga Batnyam, Babak Nazer, Matthew J Nyflot
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13576714

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