A Multicenter Non‐Inferiority Randomized Controlled Trial of Sentinel Lymph Node Biopsy in Early Breast Cancer: Conventional Dual Tracer Versus Superparamagnetic Iron Oxide

Chiu Hoi Woon Tiffany, Ray Ka Wai Hung, Kong Wai Chung Angela, Kwok Sin Man, Sheung Robin Lok Man, Violet Yee Kei Tsoi · 2026

Read A Multicenter Non‐Inferiority Randomized Controlled Trial of Sentinel Lymph Node Biopsy in Early Breast Cancer: Conventional Dual Tracer Versus Superparamagnetic Iron Oxide by Chiu Hoi Woon Tiffany, Ray Ka Wai Hung, Kong Wai Chung Angela, Kwok Sin Man, Sheung Robin Lok Man, Violet Yee Kei Tsoi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13576606.txt.

Description

Chiu and colleagues published a 2026 trial on a magnetic tracer for breast cancer surgery. Surgeons check the first lymph node, the sentinel node, to stage early breast cancer. The standard method pairs a radioactive tracer with a blue dye. The trial tested iron oxide particles that a magnet probe can find instead.

Nearly 300 patients were split between the magnetic tracer and the standard pair. The magnetic method found the sentinel node in over 99 percent of cases. The standard pair scored a perfect rate, a gap within the set limit. One failure occurred in the magnetic group across 153 procedures. The authors back the magnetic tracer as a sound stand-in option. The trial ran from 2021 to 2024 across several hospital centers.

Catalog record

CREATORChiu Hoi Woon Tiffany, Ray Ka Wai Hung, Kong Wai Chung Angela, Kwok Sin Man, Sheung Robin Lok Man, Violet Yee Kei Tsoi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13576606

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