Investigation of atypical microbial agents in patients with sterile pyuria
Elif Seren Tanrıverdi, Yusuf Yakupoğulları, Ayten Gündüz, Barış Otlu · 2026
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Description
Elif Seren Tanrıverdi and three colleagues hunt for hidden microbes in patients whose urine shows white cells yet grows nothing in culture, a pattern called sterile pyuria, in a 2026 study. Standard culture misses organisms that grow poorly in the lab. The team ran a DNA test for 14 candidate pathogens on samples from two university hospitals.
Urine came from 201 patients with the pattern and 180 controls without it. The DNA test found at least one candidate organism in 50.2 percent of patients against 10 percent of controls. Ureaplasma urealyticum led the list, ahead of Mycoplasma hominis and Gardnerella vaginalis, mostly in adult women. Higher white cell counts linked strongly to positive tests and to doctors starting treatment. The authors say these organisms deserve clinical attention, judged case by case.
Catalog record
| CREATOR | Elif Seren Tanrıverdi, Yusuf Yakupoğulları, Ayten Gündüz, Barış Otlu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33882 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |