Frequency of depression and anxiety in patients with inborn errors of immunity: a cross-sectional study

Luca J Wolff, Torsten Witte, Kai G Kahl, Anna Meinecke, Gerrit Ahrenstorf, Georgios Sogkas, Stefanie Hillmer, Thea Thiele · 2026

Read Frequency of depression and anxiety in patients with inborn errors of immunity: a cross-sectional study by Luca J Wolff, Torsten Witte, Kai G Kahl, Anna Meinecke, Gerrit Ahrenstorf, Georgios Sogkas, Stefanie Hillmer, Thea Thiele (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13576266.txt.

Description

Luca Wolff and colleagues measure how often depression and anxiety affect people born with immune system defects. Their 2026 cross-sectional study in Germany links mental health symptoms to self-isolation driven by infection fears.

One hundred forty-three patients completed standard depression and anxiety questionnaires plus ratings of fatigue, pain, and quality of life. Median symptom scores sat at the mild threshold for both conditions. About a quarter of patients with relevant symptoms had never received a diagnosis or treatment. Eleven patients scoring above the clinical cut-off had no psychiatric diagnosis recorded. Patients who self-isolated over infection concerns scored significantly higher on both symptom scales, with moderate correlations throughout.

Catalog record

CREATORLuca J Wolff, Torsten Witte, Kai G Kahl, Anna Meinecke, Gerrit Ahrenstorf, Georgios Sogkas, Stefanie Hillmer, Thea Thiele
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13576266

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