A note on a generalized single step theory for any number of hierarchical genomic matrices

Miguel Pérez-Enciso · 2026

Read A note on a generalized single step theory for any number of hierarchical genomic matrices by Miguel Pérez-Enciso (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13576223.txt.

Description

Miguel Pérez-Enciso writes a short methods note on breeding values from mixed genetic data, published in 2026. The single step method blends animals with and without DNA records, as long as a family tree links them.

The old method allowed only one set of DNA markers. Farms and labs now hold several layers, from cheap chips to full sequences. The generalized version in this note handles any number of such layers without filling in the gaps by imputation. It works down from the densest layer, and the author proves a fast inversion still exists. Tests with simulated data show better predictions than the standard method. Code is shared so others can try their own cases.

Catalog record

CREATORMiguel Pérez-Enciso
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13576223

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