Identification of a novel HIV-1 circulating recombinant form (CRF209_cpx) and its descendant unique recombinant form (URF) CRF209_cpx/B among MSM in Guangdong, southern China
Yaqing Lin, Liting Zhang, Haohui Deng, Pinfu Lai, Linna Liu, Xuemei Ling, Peng Qian, Haisheng Yu, Linghua Li, Ruolei Xin, Yun Lan · 2026
Read Identification of a novel HIV-1 circulating recombinant form (CRF209_cpx) and its descendant unique recombinant form (URF) CRF209_cpx/B among MSM in Guangdong, southern China by Yaqing Lin, Liting Zhang, Haohui Deng, Pinfu Lai, Linna Liu, Xuemei Ling, Peng Qian, Haisheng Yu, Linghua Li, Ruolei Xin, Yun Lan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13576128.txt.
Description
Yaqing Lin leads a 2026 report of a new HIV variant found in Guangdong, southern China. When several HIV strains circulate together, they can swap gene segments and create recombinant forms. Surveillance for drug resistance before treatment picked up unusual strains among men who have sex with men.
Near-complete genomes from four people defined a new circulating form, CRF209_cpx, built from three parents: CRF01_AE, CRF07_BC, and subtype B. Family-tree analysis dated its origin to between 2011 and 2013. A fifth strain mixed the new form with subtype B again. No passed-on drug resistance appeared in the five sequences. Most used the CXCR4 entry route into cells. The authors call for stronger molecular surveillance in this population.
Catalog record
| CREATOR | Yaqing Lin, Liting Zhang, Haohui Deng, Pinfu Lai, Linna Liu, Xuemei Ling, Peng Qian, Haisheng Yu, Linghua Li, Ruolei Xin, Yun Lan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24799 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |