PGC-1α and PPARs cooperatively mediate photoreceptor neuroprotection in rd1 mouse inherited retinal degeneration
Lan Wang, Jie Yan, Javier Sancho-Pelluz, Qianlu Yang, Zhulin Hu, Kangwei Jiao, Mathias W. Seeliger, François Paquet-Durand · 2026
Read PGC-1α and PPARs cooperatively mediate photoreceptor neuroprotection in rd1 mouse inherited retinal degeneration by Lan Wang, Jie Yan, Javier Sancho-Pelluz, Qianlu Yang, Zhulin Hu, Kangwei Jiao, Mathias W. Seeliger, François Paquet-Durand (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13575171.txt.
Description
Lan Wang and co-authors test in 2026 if energy switch drugs can guard light sense cells in a mouse form of a slow eye decay ill. The ill kills rod cells first, then cone cells, and has no cure. High energy need makes failed fuel supply a prime suspect in the loss.
Retina sheets from sick mice were kept in a dish and dosed with kin drug forms. Two receptor types and a co wake part cut cell death and a harm enzyme's work by clear spans. A third receptor type did scant. Gene reads track the shifts that came with the guard.
Catalog record
| CREATOR | Lan Wang, Jie Yan, Javier Sancho-Pelluz, Qianlu Yang, Zhulin Hu, Kangwei Jiao, Mathias W. Seeliger, François Paquet-Durand |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |