Advances in drug delivery systems for osteoarthritis therapy: exosomes, microparticles, nanoparticles, and hydrogels

Yu-Xin Chen, Fei Zhang, Ya Ding, Ming-Hui Zheng, Zhi-Ang Zhou, Lei Qiu, Yi-Xin Yu, Ying-Ying Gu, Qi-Rong Deng, Kun Guo, Feng Xu, Xiao-Bo Liao, Ling-Qing Yuan, Le-Le Liao · 2026

Read Advances in drug delivery systems for osteoarthritis therapy: exosomes, microparticles, nanoparticles, and hydrogels by Yu-Xin Chen, Fei Zhang, Ya Ding, Ming-Hui Zheng, Zhi-Ang Zhou, Lei Qiu, Yi-Xin Yu, Ying-Ying Gu, Qi-Rong Deng, Kun Guo, Feng Xu, Xiao-Bo Liao, Ling-Qing Yuan, Le-Le Liao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13575026.txt.

Description

Joint wear brings pain and stiff limbs, and Yu-Xin Chen and co-authors review fresh ways to ferry drugs straight into worn joints, in work from twenty twenty-six. Plain drug dosing by mouth or joint shot fades fast and can harm the whole body. Four ferry types get the focus: cell packets, tiny balls, nano-scale carriers, and gels.

Cell packets from stem cells help regrow joint padding and calm swelling. Tiny balls stretch the time a drug stays in the joint. Smart nano carriers free their load when they sense acid, enzymes, or cell stress cues. Gels hold drugs in place and can act as a scaffold. Most gains so far sit in lab studies, the authors note, with human proof still thin.

Catalog record

CREATORYu-Xin Chen, Fei Zhang, Ya Ding, Ming-Hui Zheng, Zhi-Ang Zhou, Lei Qiu, Yi-Xin Yu, Ying-Ying Gu, Qi-Rong Deng, Kun Guo, Feng Xu, Xiao-Bo Liao, Ling-Qing Yuan, Le-Le Liao
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE96 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13575026

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