Repeatability of AI-quantified incidental findings on lung cancer screening CT scans in the NELSON trial

Stijn Bunk, Thijs Bruins Slot, Edwin Bennink, Grigory Sidorenkov, Nils van der Velden, Niels Schurink, Félix Lades, Markus Sebald, Marjolein A. Heuvelmans, Hester A. Gietema, Joachim G. Aerts, Geertruida H. de Bock, Cornelia Schaefer-Prokop, Pim A. de Jong, Rozemarijn Vliegenthart, Firdaus A. A. Mohamed Hoesein, Stijn Bunk, Stijn Bunk, Grigory Sidorenkov, Marjolein A. Heuvelmans, Hester A. Gietema, Joachim G. Aerts, Cornelia Schaefer-Prokop, Pim A. de Jong, Rozemarijn Vliegenthart, Firdaus A. A. Mohamed Hoesein, Robin Cornelissen, Ralph Stadhouders, Jeroen G. J. van Rooij, Lianne Trap, Kristiaan Nackaerts, Walter de Wever, Mathias Prokop, Colin Jacobs, Noa Antonissen, Geertruida H. de Bock, Danrong Zhong, Harry J. M. Groen, Nils van der Velden, George S. Downward · 2026

Read Repeatability of AI-quantified incidental findings on lung cancer screening CT scans in the NELSON trial by Stijn Bunk, Thijs Bruins Slot, Edwin Bennink, Grigory Sidorenkov, Nils van der Velden, Niels Schurink, Félix Lades, Markus Sebald, Marjolein A. Heuvelmans, Hester A. Gietema, Joachim G. Aerts, Geertruida H. de Bock, Cornelia Schaefer-Prokop, Pim A. de Jong, Rozemarijn Vliegenthart, Firdaus A. A. Mohamed Hoesein, Stijn Bunk, Stijn Bunk, Grigory Sidorenkov, Marjolein A. Heuvelmans, Hester A. Gietema, Joachim G. Aerts, Cornelia Schaefer-Prokop, Pim A. de Jong, Rozemarijn Vliegenthart, Firdaus A. A. Mohamed Hoesein, Robin Cornelissen, Ralph Stadhouders, Jeroen G. J. van Rooij, Lianne Trap, Kristiaan Nackaerts, Walter de Wever, Mathias Prokop, Colin Jacobs, Noa Antonissen, Geertruida H. de Bock, Danrong Zhong, Harry J. M. Groen, Nils van der Velden, George S. Downward (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13574856.txt.

Description

Stijn Bunk, with a large team, reports a 2026 check of whether AI measures on lung screening scans stay steady on a quick rescan. Screening scans reveal far more than nodules, from artery width to bone loss, but hand-measuring all of it buries radiologists. Trust in auto-measures hinges on the same scan giving the same numbers twice.

The team ran one commercial chest tool on scan pairs from 1,436 people in a Dutch screening trial, taken at most 120 days apart. Gaps between paired reads were tiny for artery width, spine height, and the share of spongy lung. Heart calcium volume varied more, as small clumps shift the count. Agreement scores ran good to excellent across all measures, and sorting into severity bands held up well. The authors back the tool for routine screening add-ons.

Catalog record

CREATORStijn Bunk, Thijs Bruins Slot, Edwin Bennink, Grigory Sidorenkov, Nils van der Velden, Niels Schurink, Félix Lades, Markus Sebald, Marjolein A. Heuvelmans, Hester A. Gietema, Joachim G. Aerts, Geertruida H. de Bock, Cornelia Schaefer-Prokop, Pim A. de Jong, Rozemarijn Vliegenthart, Firdaus A. A. Mohamed Hoesein, Stijn Bunk, Stijn Bunk, Grigory Sidorenkov, Marjolein A. Heuvelmans, Hester A. Gietema, Joachim G. Aerts, Cornelia Schaefer-Prokop, Pim A. de Jong, Rozemarijn Vliegenthart, Firdaus A. A. Mohamed Hoesein, Robin Cornelissen, Ralph Stadhouders, Jeroen G. J. van Rooij, Lianne Trap, Kristiaan Nackaerts, Walter de Wever, Mathias Prokop, Colin Jacobs, Noa Antonissen, Geertruida H. de Bock, Danrong Zhong, Harry J. M. Groen, Nils van der Velden, George S. Downward
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38717
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13574856

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