A single-arm prospective phase I trial of 68Ga-PFBC01 PET/CT for multiple myeloma B cell maturation antigen imaging

Tingfei Gu, Zhao Chen, Bo Tang, Tianyao Wang, Qi Yang, Huihui Liu, Zeyin Liang, Qian Wang, Yang Zhang, Yuhua Sun, Mingyi Di, Tingting Yuan, Yongkang Qiu, Yimeng Du, Lele Song, Shengnan Wu, Wei Wang, Xiaojie Xu, Yujun Dong, Lei Kang · 2026

Read A single-arm prospective phase I trial of 68Ga-PFBC01 PET/CT for multiple myeloma B cell maturation antigen imaging by Tingfei Gu, Zhao Chen, Bo Tang, Tianyao Wang, Qi Yang, Huihui Liu, Zeyin Liang, Qian Wang, Yang Zhang, Yuhua Sun, Mingyi Di, Tingting Yuan, Yongkang Qiu, Yimeng Du, Lele Song, Shengnan Wu, Wei Wang, Xiaojie Xu, Yujun Dong, Lei Kang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13574143.txt.

Description

Tingfei Gu, with 19 colleagues, reports a 2026 first-stage trial of a new scan tracer for multiple myeloma. The disease grows from plasma cells, and a surface marker called BCMA is a prime drug target on them. Where BCMA sits across the whole body, and how it tracks disease, was not well mapped in living patients.

The single-arm phase I trial gives patients a gallium-tagged tracer built to bind BCMA, then reads the PET and CT scans. Safety comes first at this stage, with diagnostic performance and clinical use as the next questions. A tracer that lights up myeloma wherever it hides could guide who gets BCMA drugs and how well they work. The design is prospective, so scans and outcomes are logged by set rules. Results will judge whether wider trials are merited.

Catalog record

CREATORTingfei Gu, Zhao Chen, Bo Tang, Tianyao Wang, Qi Yang, Huihui Liu, Zeyin Liang, Qian Wang, Yang Zhang, Yuhua Sun, Mingyi Di, Tingting Yuan, Yongkang Qiu, Yimeng Du, Lele Song, Shengnan Wu, Wei Wang, Xiaojie Xu, Yujun Dong, Lei Kang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52349
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13574143

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