The Impact of Microsatellite Instability and CD8+ Tumor Infiltrating Lymphocytes on Neoadjuvant Chemotherapy Response in Colorectal Cancer: A Prospective Observational Study
Prapanca Nugraha, Yunia Sribudiani, Reno Rudiman, Susanti Susanti, Hermin Aminah Usman, Afrida Helen, Etis Primastari, Bambang Am Am Setya Sulthana, Raden Yohana Azhar, Kiki Lukman · 2026
Read The Impact of Microsatellite Instability and CD8+ Tumor Infiltrating Lymphocytes on Neoadjuvant Chemotherapy Response in Colorectal Cancer: A Prospective Observational Study by Prapanca Nugraha, Yunia Sribudiani, Reno Rudiman, Susanti Susanti, Hermin Aminah Usman, Afrida Helen, Etis Primastari, Bambang Am Am Setya Sulthana, Raden Yohana Azhar, Kiki Lukman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13573850.txt.
Description
Prapanca Nugraha, Kiki Lukman, and eight co-authors test two tumor traits as guides to chemo response in bowel cancer. Their study, from twenty twenty-six, runs at a hospital in West Java, Indonesia. One trait is microsatellite instability, a DNA repair flaw. The other is the count of killer T cells inside the tumor.
Forty-one patients who got chemo before surgery enter the study. A gene test reads the instability trait, and tissue staining counts the T cells. Response is judged by standard tumor size rules. Only a small share of tumors showed the instability trait. The team asks whether either trait foretells who shrinks on chemo.
Catalog record
| CREATOR | Prapanca Nugraha, Yunia Sribudiani, Reno Rudiman, Susanti Susanti, Hermin Aminah Usman, Afrida Helen, Etis Primastari, Bambang Am Am Setya Sulthana, Raden Yohana Azhar, Kiki Lukman |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |