Non-Bone-Derived Extracellular Vesicles in Osteoporosis: Evidence Mapping and Nanomedicine Translation
Jinyang An, Xinsai Li, Ying Yang, Yangyang Zhang, Shuyun Li, Mingming Jin, Haihong Lv · 2026
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Description
Jinyang An and co-authors mapped in 2026 a scattered young field: tiny parcels called extracellular vesicles, shed by tissues other than bone, and their roles in osteoporosis. Such parcels might sway bone rebuilding, serve as blood markers, or carry drugs. The team sorted 114 studies by purpose and graded their evidence and maturity.
Most work is preclinical; only fourteen studies reached evidence in human participants, and none reached the clinic or industry stage. Claims often blur: proving a parcel matters is not proving its cargo or its source did. Human marker validation and dose tracking were rare. The authors offer the map as a discipline tool. They list the proofs the field must produce before any product talk.
Catalog record
| CREATOR | Jinyang An, Xinsai Li, Ying Yang, Yangyang Zhang, Shuyun Li, Mingming Jin, Haihong Lv |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 121 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |