Electrospun core–shell nanofibres embedding drug nanocrystals for long-acting mucosal delivery
Gaia Zucca, Barbara Vigani, Caterina Valentino, Lucia Lopez-Vidal, Martina Sangalli, Marco Ruggeri, Giuseppina Sandri, Silvia Rossi, Alejandro J. Paredes · 2026
Read Electrospun core–shell nanofibres embedding drug nanocrystals for long-acting mucosal delivery by Gaia Zucca, Barbara Vigani, Caterina Valentino, Lucia Lopez-Vidal, Martina Sangalli, Marco Ruggeri, Giuseppina Sandri, Silvia Rossi, Alejandro J. Paredes (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13573742.txt.
Description
Gaia Zucca and eight co-authors report a 2026 study of electrospun core-shell fibres that hold drug nanocrystals for long use in the mouth. Mouth sores from cancer therapy are a common and sore side effect. Past local care is washed away fast, so the drug does not stay where it is needed.
The drug here is naringenin, ground to nanocrystals to help it dissolve. The crystals sit in the core of fibres spun by an electric field. A shell slows their release, and a sticky coat helps the fibre cling to the mouth lining. The plan gives a local dose that lasts.
Catalog record
| CREATOR | Gaia Zucca, Barbara Vigani, Caterina Valentino, Lucia Lopez-Vidal, Martina Sangalli, Marco Ruggeri, Giuseppina Sandri, Silvia Rossi, Alejandro J. Paredes |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |