Integrated 3D light sheet and 2D multiplex imaging for deep histological characterization of somatic mouse glioblastoma
Marie Catherine Tiveron, Nathalie Coré, Kevin Bigott, Yliana Huriaux Fontana, Maria Caccavale, Léna Vilvandre, Fabio El Yassouri, Victoria Schoppel, Silvia Rüberg, Melanie Jungblut, Dominique Figarella-Branger, Aurélie Tchoghandjian, Andreas Bosio, Harold Cremer · 2026
Read Integrated 3D light sheet and 2D multiplex imaging for deep histological characterization of somatic mouse glioblastoma by Marie Catherine Tiveron, Nathalie Coré, Kevin Bigott, Yliana Huriaux Fontana, Maria Caccavale, Léna Vilvandre, Fabio El Yassouri, Victoria Schoppel, Silvia Rüberg, Melanie Jungblut, Dominique Figarella-Branger, Aurélie Tchoghandjian, Andreas Bosio, Harold Cremer (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13573706.txt.
Description
Marie Catherine Tiveron and co-authors combine three dimensional and multiplex imaging to profile a mouse glioblastoma model, in a 2026 paper. Survival in this brain cancer has barely moved in decades, so better models and tools are needed. Stem cell based somatic models exist and are well read by sequencing, but their tissue study lagged.
Whole brain light sheet imaging showed the model grows in a highly repeatable way, letting tumor growth be measured across groups. Cyclic staining then mapped the cell types and molecular layout of the tumors and their setting, with a vetted antibody set for mouse tissue. The two imaging modes join smoothly, giving spatial protein data in three dimensions.
Catalog record
| CREATOR | Marie Catherine Tiveron, Nathalie Coré, Kevin Bigott, Yliana Huriaux Fontana, Maria Caccavale, Léna Vilvandre, Fabio El Yassouri, Victoria Schoppel, Silvia Rüberg, Melanie Jungblut, Dominique Figarella-Branger, Aurélie Tchoghandjian, Andreas Bosio, Harold Cremer |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |