Biologic Therapies for Knee Osteoarthritis: A Structured Narrative Review of Joint Preservation Strategies and Clinical Outcomes
Santiago Aguayo-Pigeonutt, Alan Mendoza-Castañeda, Iker Fernández-Ugalde, Kepler Garcia-Noriega, Santiago Flores-Cabrera, María-Fernanda Gallegos-Sánchez, Miranda Freijo-Valdovinos, Airam A Arias Villaverde, Rodrigo Anaya-Eulogio, José Emiliano González Flores · 2026
Read Biologic Therapies for Knee Osteoarthritis: A Structured Narrative Review of Joint Preservation Strategies and Clinical Outcomes by Santiago Aguayo-Pigeonutt, Alan Mendoza-Castañeda, Iker Fernández-Ugalde, Kepler Garcia-Noriega, Santiago Flores-Cabrera, María-Fernanda Gallegos-Sánchez, Miranda Freijo-Valdovinos, Airam A Arias Villaverde, Rodrigo Anaya-Eulogio, José Emiliano González Flores (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13573642.txt.
Description
Santiago Aguayo-Pigeonutt and co-authors reviewed biologic treatments for knee osteoarthritis in a 2026 narrative review. Worn knee joints cause chronic pain and disability worldwide, and standard care mostly eases symptoms rather than slowing the disease. Biologic options, made from the patient's own blood or tissues, aim to calm the joint and delay surgery.
Searching three major databases, the authors weighed platelet-rich plasma, stem-cell based treatments, and concentrated bone marrow. The evidence suggests real gains in pain and function for well-chosen patients, above all as add-ons inside a personal plan. But products and methods vary so much between clinics that results are hard to repeat or compare. Long-term effects on the joint itself remain unproven. The authors call for cleaner trials and shared standards.
Catalog record
| CREATOR | Santiago Aguayo-Pigeonutt, Alan Mendoza-Castañeda, Iker Fernández-Ugalde, Kepler Garcia-Noriega, Santiago Flores-Cabrera, María-Fernanda Gallegos-Sánchez, Miranda Freijo-Valdovinos, Airam A Arias Villaverde, Rodrigo Anaya-Eulogio, José Emiliano González Flores |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |