Glycine as a potential neuroprotective adjuvant to reduce cisplatin-induced brain inflammation in mice
Hafiz Muhammad Obaid Kazmi, Muhammad Umer Suleman, Syeda Iqra Maqsood, Shahbaz Azam Khan, Iqra Khadam, Saima Mumtaz Khattak, Umer Khalil, Muhammad Mursaleen, Muhammad Mustafeez Waheed Jami, Sumaira Javed, Najeeb Ullah, Muhammad Ikram, Marwan Alqumbaey · 2026
Read Glycine as a potential neuroprotective adjuvant to reduce cisplatin-induced brain inflammation in mice by Hafiz Muhammad Obaid Kazmi, Muhammad Umer Suleman, Syeda Iqra Maqsood, Shahbaz Azam Khan, Iqra Khadam, Saima Mumtaz Khattak, Umer Khalil, Muhammad Mursaleen, Muhammad Mustafeez Waheed Jami, Sumaira Javed, Najeeb Ullah, Muhammad Ikram, Marwan Alqumbaey (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13573425.txt.
Description
Hafiz Muhammad Obaid Kazmi, with 12 colleagues, reports a 2026 mouse study of glycine as a shield against brain harm from a cancer drug. Cisplatin cures many cancers but inflames the brain, above all the memory centre and the front cortex. Glycine, a simple amino acid, fights inflammation and oxidation and costs little.
Twenty-five male mice were split into five groups with varied timing of the drug and glycine over 14 or 28 days. Blood levels of a key inflammatory signal rose most in the long drug-only group. Glycine given alongside the drug held that signal lowest, and late glycine still helped. Brain slices showed nerve cells better preserved in glycine groups than in drug-only groups. The authors back wider preclinical tests of glycine as an add-on shield.
Catalog record
| CREATOR | Hafiz Muhammad Obaid Kazmi, Muhammad Umer Suleman, Syeda Iqra Maqsood, Shahbaz Azam Khan, Iqra Khadam, Saima Mumtaz Khattak, Umer Khalil, Muhammad Mursaleen, Muhammad Mustafeez Waheed Jami, Sumaira Javed, Najeeb Ullah, Muhammad Ikram, Marwan Alqumbaey |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40964 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |