Bio-hybrid nanovesicles with multimodal antioxidant and immunomodulatory functions attenuate acute kidney injury
Wenzhe Chen, Haitao Yuan, Haitao Liu, Min Zou, Junhui Chen, Yanting Liang, Xiaoxian Wang, Jingbo Ma, Mengyun Hou, Jinyue He, Wei Xiao, Di Gu, Guohua Zeng, Jigang Wang · 2026
Read Bio-hybrid nanovesicles with multimodal antioxidant and immunomodulatory functions attenuate acute kidney injury by Wenzhe Chen, Haitao Yuan, Haitao Liu, Min Zou, Junhui Chen, Yanting Liang, Xiaoxian Wang, Jingbo Ma, Mengyun Hou, Jinyue He, Wei Xiao, Di Gu, Guohua Zeng, Jigang Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13573420.txt.
Description
Wenzhe Chen, with 13 colleagues, presents a 2026 design for hybrid nano bubbles that treat sudden kidney injury. Such injury often follows a flood of reactive oxygen that burns kidney tubules and fires up inflammation. Single drugs rarely calm both fronts, so the team fused two helpers into one carrier.
The bubbles join vesicles shed by umbilical cord stem cells with particles of a green tea compound and a selenium amino acid. In cell tests, the hybrids cut oxidative stress, shielded cell powerhouses, and steered immune cells toward a calm state. In animals, kidney function improved and damaged tissue repaired better than with either part alone. Gene reads showed less DNA damage stress as well. The authors lay the work as a base for clinical translation.
Catalog record
| CREATOR | Wenzhe Chen, Haitao Yuan, Haitao Liu, Min Zou, Junhui Chen, Yanting Liang, Xiaoxian Wang, Jingbo Ma, Mengyun Hou, Jinyue He, Wei Xiao, Di Gu, Guohua Zeng, Jigang Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70662 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |