Early adverse events and patient-reported outcomes after salvage radiotherapy following prostatectomy according to fractionation schedule: Interim analysis of the phase III URONCOR 06–24 trial
Felipe Couñago, Carmen González, Alfonso Gómez-Iturriaga, Ana Álvarez, Marina Santos, Ana Boladeras, Nagore García, Sandra Fernández, Sandra Guardado, Abrahams Ocanto, Daniela Gonsalves, Luis Glaría, Ana Castaño, Patricia Martín, Laura Montezuma, Arantxa Mera, Joel Mases, Gerard Meca, Víctor Duque-S · 2026
Read Early adverse events and patient-reported outcomes after salvage radiotherapy following prostatectomy according to fractionation schedule: Interim analysis of the phase III URONCOR 06–24 trial by Felipe Couñago, Carmen González, Alfonso Gómez-Iturriaga, Ana Álvarez, Marina Santos, Ana Boladeras, Nagore García, Sandra Fernández, Sandra Guardado, Abrahams Ocanto, Daniela Gonsalves, Luis Glaría, Ana Castaño, Patricia Martín, Laura Montezuma, Arantxa Mera, Joel Mases, Gerard Meca, Víctor Duque-S (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13572738.txt.
Description
Felipe Couñago and a large trial team report early side effects of salvage radiation after prostate surgery, comparing dose schedules, in an interim analysis from 2026. When prostate cancer returns after removal, radiation to the surgical bed is standard. Giving it in fewer, larger doses is tempting, but proof in this setting is thin.
The phase III URONCOR trial randomized patients to moderate hypofractionation or the classic daily schedule. This early look covers the first 250 patients, most on the shorter schedule, with a median follow-up near thirteen months. Moderate urinary side effects appeared in 21.7 percent of the shorter-schedule group versus 17.3 percent on the classic plan. Patient questionnaires on urinary, bowel, and quality-of-life outcomes were collected at set points for later comparison.
Catalog record
| CREATOR | Felipe Couñago, Carmen González, Alfonso Gómez-Iturriaga, Ana Álvarez, Marina Santos, Ana Boladeras, Nagore García, Sandra Fernández, Sandra Guardado, Abrahams Ocanto, Daniela Gonsalves, Luis Glaría, Ana Castaño, Patricia Martín, Laura Montezuma, Arantxa Mera, Joel Mases, Gerard Meca, Víctor Duque-S |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |