Persistent perinatal protein malnutrition and post-weaning high-fat diet induce metabolic syndrome and hepatic UCP2 overexpression in IUGR offspring
Qiong Zeng, Yixi Wu, Yanting Chen, Qing Li, Zhijian Deng, Xiutong Chen, Jingsa Wang, Yiting He, Zeming Ma, Runjia Yang, Kun Lin · 2026
Read Persistent perinatal protein malnutrition and post-weaning high-fat diet induce metabolic syndrome and hepatic UCP2 overexpression in IUGR offspring by Qiong Zeng, Yixi Wu, Yanting Chen, Qing Li, Zhijian Deng, Xiutong Chen, Jingsa Wang, Yiting He, Zeming Ma, Runjia Yang, Kun Lin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13572690.txt.
Description
Qiong Zeng and co-authors test how food in the womb and in youth shapes the health of stunted pups, in a 2026 rat study. Babies born small face a high risk of the cluster of ills known as metabolic syndrome as adults.
The team fed mother rats a low-protein diet, then set the male pups on one of five food paths. At twelve weeks, one path stood out. Pups held on thin fare through birth and nursing, then fed fat-rich food, grew fat at the waist. They lost sugar control and built up fat in the liver. Pups fed well after birth were largely spared, even on rich food. A liver protein ran high in the hit group. The authors call the span a two-hit path and press the case for early food repair.
Catalog record
| CREATOR | Qiong Zeng, Yixi Wu, Yanting Chen, Qing Li, Zhijian Deng, Xiutong Chen, Jingsa Wang, Yiting He, Zeming Ma, Runjia Yang, Kun Lin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |