Ultra-hypofractionation versus standard hypofractionation in post-mastectomy radiotherapy (PMRT): a prospective randomised dosimetric and clinical comparison study

Meghal Prajapati, Anil Kumar Goel, Yamini Patel, Divyeshkumar Rana, S Lokesh, Pooja Panchal, Dhruv Rathod, Chandramouli Ramalingam, Kondeti Ajay Kumar · 2026

Read Ultra-hypofractionation versus standard hypofractionation in post-mastectomy radiotherapy (PMRT): a prospective randomised dosimetric and clinical comparison study by Meghal Prajapati, Anil Kumar Goel, Yamini Patel, Divyeshkumar Rana, S Lokesh, Pooja Panchal, Dhruv Rathod, Chandramouli Ramalingam, Kondeti Ajay Kumar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572568.txt.

Description

Meghal Prajapati, with eight colleagues, reports a 2026 trial of shorter radiation courses after mastectomy in India. Radiation after breast removal cuts return of the cancer, yet long courses burden patients and clinics. Trials abroad set a 15-visit course as safe, and a 5-visit course worked in trials where few women had mastectomy.

Fifty women with stage II to IIIA cancer were assigned at random to 40 gray in 15 visits or 26 gray in 5 visits. Both courses covered the target well, above 95 percent. The short course spared the near lung, far lung, other breast, and spinal cord more. Heart dose ran a bit higher, yet stayed well within safe bounds, helped by a breath-hold trick for left-side cases. Skin harm was mild in both groups, and all women were alive and disease-free at six months.

Catalog record

CREATORMeghal Prajapati, Anil Kumar Goel, Yamini Patel, Divyeshkumar Rana, S Lokesh, Pooja Panchal, Dhruv Rathod, Chandramouli Ramalingam, Kondeti Ajay Kumar
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33494
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13572568

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