Hydrogen sulfide inhalation induces changes in body physiology and lung gene expression in mice

Jun Lei Gao, Bai Hao Li, Zhi Bin Ban, Li Jia Li, Hao Liang, Xiao Gang Yan, Cheng Xiao, Fang Yu Zhang · 2026

Read Hydrogen sulfide inhalation induces changes in body physiology and lung gene expression in mice by Jun Lei Gao, Bai Hao Li, Zhi Bin Ban, Li Jia Li, Hao Liang, Xiao Gang Yan, Cheng Xiao, Fang Yu Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572558.txt.

Description

Jun Lei Gao, with seven colleagues, reports a 2026 mouse study of breathing hydrogen sulfide, a toxic gas found in industry and farm waste. The gas can harm the lungs, immune system, and nerves, but the gene-level picture in lung tissue was unclear. The team varied the dose and read both body markers and lung gene activity.

At set doses, the gas raised an inflammatory signal and two defence enzymes, while high doses shifted more immune signals and stress measures. Some markers of cell damage fell, a mixed pattern the authors note. Lung gene reads found 963 genes whose levels changed across groups. Those genes cluster in immune response, DNA change, enzyme work, and cell cycle control. Four genes, among them FGFBP1 and GATA3, look central to the response. The data set seeds later work on how the gas harms lungs.

Catalog record

CREATORJun Lei Gao, Bai Hao Li, Zhi Bin Ban, Li Jia Li, Hao Liang, Xiao Gang Yan, Cheng Xiao, Fang Yu Zhang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43833
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13572558

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