Association between risk-related lifestyle factors, screening adherence and breast cancer incidence: a decomposition analysis
Md Sohel Rana, M Luke Marinovich, Nehmat Houssami, Dominic Cavenagh, Julie E Byles, Xue Qin Yu, Md Mijanur Rahman · 2026
Read Association between risk-related lifestyle factors, screening adherence and breast cancer incidence: a decomposition analysis by Md Sohel Rana, M Luke Marinovich, Nehmat Houssami, Dominic Cavenagh, Julie E Byles, Xue Qin Yu, Md Mijanur Rahman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572556.txt.
Description
Md Sohel Rana, with six colleagues, reports a 2026 study that splits the link between lifestyle and breast cancer into direct and screening paths. Women who follow screening may differ in habits, and screening itself finds cancers earlier. The team asked how much of the lifestyle effect runs through screening adherence.
The cohort followed 10,579 women from ages 50 to 55 in 2001 through 2019, when 571 developed breast cancer. A four-way split method separated direct effects from those passed through screening. Higher body mass, alcohol use, and hormone therapy each raised overall risk. Direct effects stayed for body mass and alcohol after the split. Small indirect paths ran through screening for alcohol and hormone therapy. Oral contraceptive use showed a negative direct effect.
Catalog record
| CREATOR | Md Sohel Rana, M Luke Marinovich, Nehmat Houssami, Dominic Cavenagh, Julie E Byles, Xue Qin Yu, Md Mijanur Rahman |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33453 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |