Therapeutic efficacy, safety and gametocyte clearance after antimalarial treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax malaria in Northeast Ethiopia

Habtu Debash, Mihret Tilahun, Sisay Desale, Emiyamrew Getnet, Abdurehman Eshete Mohammed · 2026

Read Therapeutic efficacy, safety and gametocyte clearance after antimalarial treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax malaria in Northeast Ethiopia by Habtu Debash, Mihret Tilahun, Sisay Desale, Emiyamrew Getnet, Abdurehman Eshete Mohammed (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572463.txt.

Description

Habtu Debash, with four colleagues, reports on a 2026 study of malaria drug performance in northeast Ethiopia. Two parasite species cause most cases there, and health teams must watch whether first-line drugs still work. The team also tracked how fast the sex forms of the parasite, which pass malaria to mosquitoes, clear after treatment.

From November 2024 to January 2026, 159 patients with mild malaria were followed for 28 days. One species was treated with artemether-lumefantrine and the other with chloroquine, and some patients got a low dose of primaquine as well. Cure rates were 88.9 and 97.4 percent for the two species. Fever and parasites cleared faster in the second species. Primaquine cut sex-form clearance time in one species from eleven days to seven, and from seven to four in the other. Side effects stayed mild.

Catalog record

CREATORHabtu Debash, Mihret Tilahun, Sisay Desale, Emiyamrew Getnet, Abdurehman Eshete Mohammed
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41813
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13572463

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