Metaproteomic profiling reveals viral proteins and associated host proteomic alterations in glioblastoma
Bavani Gunasegaran, Shivani Krishnamurthy, Seong Beom Ahn, Benjamin Heng · 2026
Read Metaproteomic profiling reveals viral proteins and associated host proteomic alterations in glioblastoma by Bavani Gunasegaran, Shivani Krishnamurthy, Seong Beom Ahn, Benjamin Heng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572378.txt.
Description
Bavani Gunasegaran, with three colleagues, reports a 2026 study that hunts for virus proteins inside glioblastoma, a fast and deadly brain tumour. Whether viruses play a role in this cancer has long been unclear. Tests in past work gave mixed results, in part due to the limits of each tool.
The team ran a protein-wide scan on tumour and control tissue from a public data set of 192 samples. A second group of 81 samples served as a check. Virus proteins from many species turned up, and human herpesviruses 1, 2, and 8 showed up more often in tumours than in controls. Host proteins tied to gene control, RNA handling, and energy use in cells also shifted. Links between virus and host proteins hint at paths for later work.
Catalog record
| CREATOR | Bavani Gunasegaran, Shivani Krishnamurthy, Seong Beom Ahn, Benjamin Heng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71395 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |