The burden and unique patterns of extraintestinal manifestations in Chinese inflammatory bowel disease: a nationwide multicenter investigation

Liuqing Zhao, Zhenzhen Fan, Jindan He, Lianlian Tian, Jun Shen, Hongliang Gao, Yanjun Chen, Xiaojing Zhao, Yan-Bo Yu, Yanyun Fan, Haitao Shi, Hailong Cao, Linglin Tian, Jie Liang · 2026

Read The burden and unique patterns of extraintestinal manifestations in Chinese inflammatory bowel disease: a nationwide multicenter investigation by Liuqing Zhao, Zhenzhen Fan, Jindan He, Lianlian Tian, Jun Shen, Hongliang Gao, Yanjun Chen, Xiaojing Zhao, Yan-Bo Yu, Yanyun Fan, Haitao Shi, Hailong Cao, Linglin Tian, Jie Liang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572327.txt.

Description

Liuqing Zhao and colleagues survey, in a 2026 nationwide multicenter study, problems outside the gut in 2,252 Chinese inpatients with inflammatory bowel disease across ten centers. Such extra-intestinal problems, from joint pain to eye and skin inflammation, add heavy burden, yet large Chinese data were scarce.

About seventeen percent reported at least one such problem, more in Crohn's disease than in ulcerative colitis. Joint complaints and mouth ulcers led the list, and mouth ulcers clustered strongly in Crohn's disease. Problems often traveled together, with joint disease tied strikingly to eye and skin conditions. In about a fifth of timed cases, the outside problem arrived before bowel symptoms, a warning for doctors chasing unexplained joint or eye inflammation.

Catalog record

CREATORLiuqing Zhao, Zhenzhen Fan, Jindan He, Lianlian Tian, Jun Shen, Hongliang Gao, Yanjun Chen, Xiaojing Zhao, Yan-Bo Yu, Yanyun Fan, Haitao Shi, Hailong Cao, Linglin Tian, Jie Liang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37341
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13572327

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