Is a history of cesarean section a predictive factor for the failure of medical management in spontaneous abortion?

Ravit Pertez-Machluf, Maya Youran Kimhi, Rotem Yedidia Moser, Nissim Arbib, Yair Daykan, Omer Weitzner, Ron Schonman, Zvi Klein, Yael Yagur · 2026

Read Is a history of cesarean section a predictive factor for the failure of medical management in spontaneous abortion? by Ravit Pertez-Machluf, Maya Youran Kimhi, Rotem Yedidia Moser, Nissim Arbib, Yair Daykan, Omer Weitzner, Ron Schonman, Zvi Klein, Yael Yagur (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572325.txt.

Description

Ravit Pertez-Machluf and colleagues ask, in a 2026 retrospective study, whether a past cesarean birth predicts failure of drug treatment for first-trimester miscarriage. Records covered 716 patients treated with mifepristone and misoprostol at a major center between 2019 and 2022, comparing those whose treatment completed against those needing further intervention.

Treatment failed in just under thirty percent. A prior cesarean nearly doubled the adjusted odds of failure, and each extra day of pregnancy age added a little risk. Failure rates ran higher still in the cesarean subgroup analysis. Among women without a cesarean history and earlier pregnancies, bleeding during treatment oddly marked lower failure. Counselors can now give cesarean-scarred patients a more honest estimate before choosing drug treatment.

Catalog record

CREATORRavit Pertez-Machluf, Maya Youran Kimhi, Rotem Yedidia Moser, Nissim Arbib, Yair Daykan, Omer Weitzner, Ron Schonman, Zvi Klein, Yael Yagur
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27257
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13572325

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