Temporal trends and mortality associated with difficult-to-treat resistance in bloodstream gram-negative bacilli: a retrospective cohort study in Southern Saudi Arabia
Yahya Shabi, Ali M. Somily, Khalifa Binkhamis, Tarik Alazraqi, Safia Abdullah Mohammed, Sara Habbash, Norah Yahya Algathradi Asiri, Esmahan Tahtouh, Mona M Alshahrani, Ibrahim Tawhari, Soliuman Mohamed, Abdulah J. Alqahtani, Ihab M. Abdelrahim, Raghad Darwish, Abdulah OS Bawazeer · 2026
Read Temporal trends and mortality associated with difficult-to-treat resistance in bloodstream gram-negative bacilli: a retrospective cohort study in Southern Saudi Arabia by Yahya Shabi, Ali M. Somily, Khalifa Binkhamis, Tarik Alazraqi, Safia Abdullah Mohammed, Sara Habbash, Norah Yahya Algathradi Asiri, Esmahan Tahtouh, Mona M Alshahrani, Ibrahim Tawhari, Soliuman Mohamed, Abdulah J. Alqahtani, Ihab M. Abdelrahim, Raghad Darwish, Abdulah OS Bawazeer (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13572238.txt.
Description
Yahya Shabi and fourteen co-authors track, in 2026 work, hard-to-treat germs in blood infections at a large hospital in southern Saudi Arabia. Some bacteria in the blood no longer yield to first-line drugs. The team asked how that deep resistance grew over time and what it meant for survival.
Records from 2013 to 2024 gave more than two thousand illness cases. The mix of germs stayed much the same, but one lung germ grew more common. Resistance to key last-line drugs rose sharply, and deep resistance rose with it. About one in three patients died within a month. Deep resistance raised the risk of death in both germ groups. The team backs checks based on what drugs still work, not broad labels.
Catalog record
| CREATOR | Yahya Shabi, Ali M. Somily, Khalifa Binkhamis, Tarik Alazraqi, Safia Abdullah Mohammed, Sara Habbash, Norah Yahya Algathradi Asiri, Esmahan Tahtouh, Mona M Alshahrani, Ibrahim Tawhari, Soliuman Mohamed, Abdulah J. Alqahtani, Ihab M. Abdelrahim, Raghad Darwish, Abdulah OS Bawazeer |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |