Curcumin attenuates di(2-ethylhexyl) phthalate-induced hepatic injury in chicks via oxidative stress, glycolysis, and PANoptosis-related signaling
Xiaoyu Zhao, Bolin Zhao, Bin Li, Rong Guo, Yue Liu, Li Liu, Yue Xu, Guangxing Li, Xiaodan Huang · 2026
Read Curcumin attenuates di(2-ethylhexyl) phthalate-induced hepatic injury in chicks via oxidative stress, glycolysis, and PANoptosis-related signaling by Xiaoyu Zhao, Bolin Zhao, Bin Li, Rong Guo, Yue Liu, Li Liu, Yue Xu, Guangxing Li, Xiaodan Huang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572206.txt.
Description
Xiaoyu Zhao and co-authors test, in a 2026 study, whether curcumin, the yellow compound in turmeric, protects chick livers against a common plasticizer called DEHP that leaks from plastics into the environment. Cell experiments and live chick exposures traced damage through oxidative stress, energy production, and a mixed cell-death program.
In cells, curcumin restored mitochondrial power, calmed calcium imbalance, and eased internal stress while suppressing a sugar-burning pathway that the plasticizer switched on. Blocking that pathway lowered death markers too. In live chicks, the plasticizer shrank body weight and swelled and scarred the liver, while curcumin feeding largely reversed those changes. The findings support turmeric compounds as a feed defense where plastic contamination reaches poultry.
Catalog record
| CREATOR | Xiaoyu Zhao, Bolin Zhao, Bin Li, Rong Guo, Yue Liu, Li Liu, Yue Xu, Guangxing Li, Xiaodan Huang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |