Dynamic regulation of CD300b and CD300f on myeloid cells in oral immunotherapy
Na'ama Epstein-Rigbi, Michal Itan, Shmulik Avlas, Eytan Damari, Liat Nachshon, Yael Koren, Michael Levy, Michael R. Goldberg, Arnon Elizur, Ariel Munitz · 2026
Read Dynamic regulation of CD300b and CD300f on myeloid cells in oral immunotherapy by Na'ama Epstein-Rigbi, Michal Itan, Shmulik Avlas, Eytan Damari, Liat Nachshon, Yael Koren, Michael Levy, Michael R. Goldberg, Arnon Elizur, Ariel Munitz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13572044.txt.
Description
Na'ama Epstein-Rigbi and colleagues examine, in a 2026 study, how two receptors on innate immune cells shift during oral immunotherapy for food allergy. This treatment feeds patients slowly rising doses of the food they react to. Such therapy can desensitize patients and sometimes leave lasting tolerance, driven mainly by regulatory T cells and calming signals, while the role of front-line cells such as eosinophils and monocytes stayed unclear.
The receptors under study belong to the CD300 family, one activating and one inhibitory, both sensing fatty molecules on cell surfaces. Tracking their levels during therapy tests whether these cells merely follow the calmer environment or actively help build tolerance. The answer could reveal new markers for judging whether treatment is working.
Catalog record
| CREATOR | Na'ama Epstein-Rigbi, Michal Itan, Shmulik Avlas, Eytan Damari, Liat Nachshon, Yael Koren, Michael Levy, Michael R. Goldberg, Arnon Elizur, Ariel Munitz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |