Orbital tumor in DICER1 syndrome (embryonal tumor with multilayered rosettes) successfully treated with intraarterial chemotherapy
David H. Abramson, Leonard Wexler, Michelle Maeng, Juan C. Vasquez, David Della Rocca, Jasmine H. Francis, Lisa Koenig, Jamal Benhamida, Marc Rosenblum, Y. Pierre Gobin · 2026
Read Orbital tumor in DICER1 syndrome (embryonal tumor with multilayered rosettes) successfully treated with intraarterial chemotherapy by David H. Abramson, Leonard Wexler, Michelle Maeng, Juan C. Vasquez, David Della Rocca, Jasmine H. Francis, Lisa Koenig, Jamal Benhamida, Marc Rosenblum, Y. Pierre Gobin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571946.txt.
Description
David Abramson and co-authors report treating a baby's orbital tumor with artery-delivered chemotherapy in this 2026 case paper. The child carried DICER1 syndrome, a genetic condition tied to several tumors. Eye tumors in that syndrome are known, but orbital ones are rare. A scan at one month old showed an orbital mass. It was first taken for a common benign blood vessel growth. Standard medicine for that guess brought no response.
Further work revealed an aggressive embryonal tumor instead. Genetic faults, inherited and in the tumor, fit the syndrome. Chemotherapy was delivered straight into the artery feeding the tumor. That route concentrates the drug where it is needed. The title reports the treatment succeeded. The case warns against trusting first impressions in infant eye masses.
Catalog record
| CREATOR | David H. Abramson, Leonard Wexler, Michelle Maeng, Juan C. Vasquez, David Della Rocca, Jasmine H. Francis, Lisa Koenig, Jamal Benhamida, Marc Rosenblum, Y. Pierre Gobin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |