In situ Gel–Nano transformable hydrogel for therapeutic intervention in refractory inflammation-related trauma
Jingxuan Xu, Yifeng Zhu, Guangjian Fan, Yaoyao Li, Yuxiang Zhang, Bowen Li, Wenwei Cai, Chenyue Zhan · 2026
Read In situ Gel–Nano transformable hydrogel for therapeutic intervention in refractory inflammation-related trauma by Jingxuan Xu, Yifeng Zhu, Guangjian Fan, Yaoyao Li, Yuxiang Zhang, Bowen Li, Wenwei Cai, Chenyue Zhan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571723.txt.
Description
Jingxuan Xu and co-authors present an injectable gel that turns into nanoparticles at injured sites in a 2026 paper. The gel targets wounds and inflamed tissue that resist standard care. It carries a high load of dopamine, a substance that can both form the gel and, once released, build drug loaded particles on the spot.
The gel stays where it is placed and responds to the local state of the tissue. It soaks up excess reactive oxygen, calms swelling, and releases its particles over time. Tests included use in the brain after a stroke like injury and on skin grafts. The authors frame the gel as a local, lasting, and responsive therapy platform.
Catalog record
| CREATOR | Jingxuan Xu, Yifeng Zhu, Guangjian Fan, Yaoyao Li, Yuxiang Zhang, Bowen Li, Wenwei Cai, Chenyue Zhan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |