Regulated Cell Death at the Maternal-Fetal Interface in Preeclampsia: Apoptosis, Necroptosis, Pyroptosis, Ferroptosis, Autophagic Cell Death, and Cuproptosis - A Narrative Review
Rui Xiong, Ning Xu, Min Li, Yuanqin Gou · 2026
Read Regulated Cell Death at the Maternal-Fetal Interface in Preeclampsia: Apoptosis, Necroptosis, Pyroptosis, Ferroptosis, Autophagic Cell Death, and Cuproptosis - A Narrative Review by Rui Xiong, Ning Xu, Min Li, Yuanqin Gou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571678.txt.
Description
Rui Xiong and three co-authors review the many ways cells die at the meeting point of mother and fetus in preeclampsia, a 2026 paper. The disorder raises the mother's blood pressure and damages organs, and stressed placenta tissue drives much of it.
Six death programs are compared: quiet apoptosis, bursting necroptosis and pyroptosis, iron-driven ferroptosis, self-eating gone lethal, and copper-linked cuproptosis. Low oxygen, oxidative stress, and metal imbalance trigger them in placenta and immune cells. Their debris and alarm signals spill into the mother's blood and inflame her vessels. The review lines up each pathway's triggers, machinery, and products. An integrated model ties the pathways into one self-reinforcing loop.
Catalog record
| CREATOR | Rui Xiong, Ning Xu, Min Li, Yuanqin Gou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 90 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |