A Literature Review of Immunotherapeutics in the Management of Adult B-Cell Acute Lymphoblastic Leukemia
Tamer Othman, Ibrahim Aldoss · 2026
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Description
Tamer Othman and Ibrahim Aldoss present a 2026 literature review of immune therapies for adult B-cell acute lymphoblastic leukemia. Returned or resistant disease once left adults with poor odds, and transplant in a second remission was the only path to cure. Three immune treatments changed that picture in the last decade.
The review sums the key trials of blinatumomab, inotuzumab ozogamicin, and CAR T-cell therapy, weighing benefit and side effects for each. All three improved outcomes in returned disease while cutting reliance on harsh chemotherapy, and all are moving into first-line care. The authors add their own guidance on fitting the drugs into practice.
Catalog record
| CREATOR | Tamer Othman, Ibrahim Aldoss |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |