Overexpression of ROSMARINIC ACID SYNTHASE enhances the hepatoprotective potential of Dracocephalum heterophyllum hairy root cultures

Lu Cao, Zhenying Wu, Yingping Cao, Lichengcheng Ren, Na Hu, Yaling Liu, Yuchen Liu, Shaowei Yu, Jingzhe Sun, Meifeng Liu, Feng Yuan, Honglun Wang, Chunxiang Fu · 2026

Read Overexpression of ROSMARINIC ACID SYNTHASE enhances the hepatoprotective potential of Dracocephalum heterophyllum hairy root cultures by Lu Cao, Zhenying Wu, Yingping Cao, Lichengcheng Ren, Na Hu, Yaling Liu, Yuchen Liu, Shaowei Yu, Jingzhe Sun, Meifeng Liu, Feng Yuan, Honglun Wang, Chunxiang Fu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571569.txt.

Description

Lu Cao and co-authors boost a liver-protecting herb compound in lab-grown roots in a 2026 study. The Tibetan herb Dracocephalum heterophyllum makes rosmarinic acid, which guards the liver, but the plant grows only in harsh high places. The team built a shoot multiplication system, then grew hairy roots that can be farmed in tanks.

Inserting a synthase gene from a related plant raised the acid yield up to about twofold. The enriched roots also cut fat and protected liver cells better in dish tests. Readers get a sustainable supply route for a scarce medicinal compound.

Catalog record

CREATORLu Cao, Zhenying Wu, Yingping Cao, Lichengcheng Ren, Na Hu, Yaling Liu, Yuchen Liu, Shaowei Yu, Jingzhe Sun, Meifeng Liu, Feng Yuan, Honglun Wang, Chunxiang Fu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13571569

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